Remote Computational Pharmacokinetics & Metabolism Data Scientist

at Deep Origin

Posted 1 day ago 1 applied

Description:

  • Deep Origin is a biotechnology company focused on accelerating drug discovery through AI-powered tools.
  • The company integrates advanced computational methods with experimental data to model biological systems at scale.
  • The role is for a Data Scientist with expertise in quantitative pharmacokinetics, parameter estimation, and metabolic modeling.
  • The candidate will develop hybrid computational frameworks that combine ordinary differential equation-based (ODE-based) simulations with machine learning methods.
  • Responsibilities include predicting metabolic parameters, distribution profiles, and biotransformation outcomes.
  • This position requires strong mathematical modeling skills, statistical acumen, and experience in integrating diverse datasets into robust predictive models.
  • The role combines expertise in systems pharmacology, machine learning, and data-driven modeling to develop hybrid approaches for Deep Origin’s AI-powered metabolism and pharmacokinetic simulation platform.

Requirements:

  • A PhD (0-2 years) or MS (2-5 years) in Systems Biology, Computational Pharmacology, Applied Mathematics, or a related field is required.
  • A strong background in ODE/PDE modeling, numerical simulation, and parameter estimation is necessary.
  • Experience with pharmacokinetic model development is essential.
  • Proficiency in Python is required.
  • A basic understanding of drug metabolism and pharmacokinetics (DMPK) concepts is needed.
  • Strong statistical analysis skills and experience with Bayesian or frequentist inference methods are required.
  • The ability to critically analyze data and translate findings into actionable predictions and computational models is necessary.
  • A collaborative mindset and comfort in both autonomous and team-based settings are important.
  • Adaptability to thrive in a fast-paced, deadline-driven environment is required.

Benefits:

  • The opportunity to work on impactful problems at the intersection of AI, chemistry, and biology.
  • Collaboration with multidisciplinary teams of scientists is encouraged.
  • The chance to shape next-generation tools for predictive drug discovery is offered.